Matthew Perry's untimely demise on October 28 shook the entire world. He was 54 years old. Initial reports claimed that he passed away due to accidentally drowning in Los Angeles. Now, over a month later, the autopsy report revealed the reason behind his demise. 

On Friday, the Los Angeles County Medical Examiner’s Office revealed the details of the autopsy report. It said Matthew's demise was caused due to drowning, coronary artery disease and the effects of an opioid, buprenorphine. The autopsy also noted the role of “the acute effects of ketamine” in his death. It is an anaesthetic used for depression, anxiety, post-traumatic stress disorder and other mental health concerns. 

According to the NY Times, the autopsy report stated that Matthew had been on ketamine infusion therapy. Reports claim that the actor, known for playing the role of Chandler in Friends, had taken therapy around a week and a half before his untimely demise. 

In the NY Times report, a quote from the autopsy read, "At the high levels of ketamine found in his postmortem blood specimens, the main lethal effects would be from both cardiovascular overstimulation and respiratory depression."

Hours before his demise, Matthew returned to the room after playing pickleball. His assistant was out to run errands and he returned to find the actor drowning in the hot tub.